P-3: Effects of Increased Mast Cells Number-Induced by Sulpiride Atipycal Antipsychotic Drug on Sertoli Cells and Sperm Production in Adult Male Mice

P-4: Effect of Reduced FSH Serum Concentration Induced by Sulpiride Atypical Antipsychotic Drug on Repopulation Index and Number of Primery Spermatocyte Cells in Adult Male Mice

Background: Usage of some atipycal antipsychotic drugs like sulpiride has severed effects on male fertility by impressions on sexual hormones secretion. These hormones regulate male germ cells proliferation and differentiation. In the present study we sought to elucidate the impact of sulpiride on serum prolactin and FSH concentration. Also effect of FSH on spermatogonium A/B (repopulation inde...

P-88: Mast Cells Number and Distribution and Myoid Cells Population Are Impressed by Sulpiride Antipsychotic Drug

Background: Spermatogenesis is under the control of variety of factors, which include mast cells. Any changes in testicular mast cells’ number and distribution resulting in deterioration of comlex regulation and fine-turning of spermatogenesis. Increased number of mast cells and their abnormal spread pattern have been described in the testis with fertility disturbances. Mast cells’ tryptase enz...

P-74: Crocin Repopulate The Leydig and Sertoli Cells in Testis of Cyclophosphamide Treated Adult Mice

Background: Increases in the survival rate of men treated with chemotherapeutic drugs and their desire to have children precipitate concerns about the effects of these drugs on germ cells. This study performed to evaluation of protective effects of crocin in oxidative stress induced by cyclophosphamide (CP) on testis. Materials and Methods: Three groups (6 mice in each) of adult mice were used....

P-5: Evaluation of The Effect of Sulpiride As An Atypical Antipsychotic Drug, on The Serum Levels of Prolactin, LH, FSH and Testosterone in Adult Male Mice

Background: Prescription of the atypical antipsychotic drugs like as Sulpiride for the treatment of schizophrenic patients was increased because of their less side effects. This study was aimed to evaluate the effect of sulpiride on hormonal milieu of adult male mice namely their serum level of prolactin and sexual hormones. Materials and Methods: 24 adult male mice were divided in three groups...

P-7: Testosterone and Gonadotrophin Hormones Plasma Concentration-Induced Changes in Sertoli and Leydig Cells Number in Hyperprolactinemic Mature Male Mice

Background: Hyperprolactinemia is a particular concern in the treatment of schizophrenic patients. The side effects associated with high prolactin levels can have a negative impact on GnRH pulsatile secretion and, consequently LH, FSH and testosterone pulsatility and follows by, on special testicular cells that have these hormon’s receptors such as sertoli and leydig cells. Quantification the d...

Comparison of Neonatal and Adult Mice-derived Sertoli Cells in Support of Expansion of Mouse Spermatogonial Stem Cells In vitro